Anne Carlisle

Anne Carlisle is the wife of Gabriel Carlisle and Sorin Carlisle, and she lived with them in a small Kaldorian village 30 years ago.

Personality
Anne appears to be a stern and somewhat short tempered woman, a trait Sorin inherited. She also doesn't seem very compassionate, coldly demanding that Sorin drown Rem in the river rather than keep him. This might have, in a twisted sense, actually been a sign of mercy on Anne's part - as she believes the puppy would not survive in the wilderness, so drowning it in her mind would be the compassionate thing to do as opposed to simply abandoning it in the wild.

When chastising Sorin for being in the forest during the first Twisted attack, she becomes hysterical, indicating that she does love Sorin very much.

The Shepherd Arc
Upon returning the home from some unspecified task, Anne discovers her table bloody from Rem. hitting Sorin, Anne demands that Rem be drowned in the river. Sorin defiantly protests, angering Anne greatly, but Gabriel intervenes before she can strike Sorin again.

After the Twisted attack, Anne scolds Sorin harshly for being in the woods.

In the months after the Twisted attacks, Anne begins to form a better relationship with Rem, coming to appreciate the dog.

She escapes the village with her husband, daughter, and Rem when the walls fall, but is raped and killed by bandits shortly thereafter.